Last week I met three people with iridocyclitis caused by ankylosing spondylitis, which is related with the gene of HLA-B27. Those patients were complaining the ocular pain, red eye, weeping, photophobia and mild vision decrease. The most common cause of hypopyon uveitis in north America and Europe is HLA-B27-associated uveitis, whereas the most common cause of hypopyon uveitis in Asia is Behcet’s disease.

Up to 50% ankylosing spondylitis patients develop anterior uveitis. Especial for men. The uveitis can vary in severity from mild to severe and often produces pain, photophobia, and blurred vision. Limbal injection is often present. Keratic precipitates are More >